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NuCana plc

$1.28Last updated
-$0.04 (3.03%)Past day
Timezone

NuCana plc (NASDAQ: NCNA) is trading at $1.28, about ₹123 at today's USD/INR rate, as of 25 Sep 2026, 4:00 PM ET, down 3.03% today. Indian residents can buy NuCana from India on Paasa under the RBI's Liberalised Remittance Scheme.

Quote

Open:$1.32
Previous close:$1.32
Volume:38.07K

Today's low

$1.28

Today's high

$1.35

52 week low

$1.21

52 week high

$7.22

NCNA opened at $1.32, closed previously at $1.32, and has traded between $1.21 and $7.22 over the past 52 weeks.

About

NuCana plc is a clinical-stage biopharmaceutical firm dedicated to pioneering advanced therapies for oncology. Its innovative product pipeline is underpinned by a proprietary ProTide technology platform. Among its key drug candidates, Acelarin is progressing through multiple clinical evaluations: a Phase I study for advanced solid tumors, Phase Ib trials for both recurrent ovarian cancer and biliary tract cancer, a Phase II trial targeting platinum-resistant ovarian cancer, and a pivotal Phase III trial for pancreatic cancer. NuCana is also developing NUC-3373, a ProTide derivative of 5-fluorouracil’s active anti-cancer metabolite. This compound is currently in a Phase I study for advanced solid tumors and a Phase Ib/2 trial for advanced colorectal cancer. Additionally, NUC-7738, a nucleoside analog, is undergoing Phase 1/2 clinical assessment for both advanced solid and hematological malignancies. To support its ProTide technology development, the company maintains research, collaboration, and licensing agreements with Cardiff University and University College Cardiff Consultants Ltd., covering the design, synthesis, characterization, and assessment of these compounds. Further collaborative and licensing arrangements are in place with Cardiff ProTides Ltd. Established in 1997, the company operated as NuCana BioMed Limited before rebranding to NuCana plc in August 2017. Its corporate headquarters are located in Edinburgh, United Kingdom.

Country
GB
CEO
Hugh Stephen Griffith
Exchange listed on
NASDAQ
Industry
Biotechnology
Base currency
USD
Full Time Employees
11
Sector
Healthcare
IPO date
28/09/2017

Key statistics

Avg. volume

55.88K

Market cap

$7.77M

P/E Ratio

-0.33

Price-to-sales ratio

0.00

Enterprise value

-£12.85M

Free cash flow yield

-87.87%

Debt-to-equity ratio

0.03

Return on equity

-41.95%

ROIC

-56.59%

Beta

2.24

Dividend yield

0.00%

Last dividend

$0.00

Financial overview

Revenue

£0.00

Earnings per share

-£17.20

Free cash flow

-£7.66M

Net profit margin

0.00%

Gross margin

0.00%

EBITDA

-£20.56M

Revenue growth

—

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This is not an investment recommendation

How to buy NuCana from India

Indian residents can buy NuCana shares through Paasa in four steps. Funds leave India under the RBI's Liberalised Remittance Scheme and the shares are held in your own name with Interactive Brokers.

  1. Open a Paasa account

    Complete digital KYC with your PAN, Aadhaar and address proof. Your brokerage account is opened in your own name with Interactive Brokers.

  2. Add funds under LRS

    Transfer INR from your Indian bank account. Your bank reports the remittance under the RBI's Liberalised Remittance Scheme and converts it to US dollars.

  3. Search for NuCana and place an order

    Find NuCana by name or by its ticker, NCNA, and choose an order type. You can buy by amount or by quantity — fractional shares mean there is no minimum trade size. NuCana trades 7:00 pm – 1:30 am IST; orders can only execute during that window.

  4. Track holdings and download tax reports

    Follow your NuCana position in USD and INR. NuCana pays no dividend today, so your filing is the capital-gains statement plus the Schedule FA holding line.

Read the full guide: how to invest in NuCana from India

Trading and taxes when buying NuCana from India

Trading and limits

Trading hours
9:30 am – 4:00 pm ET
LRS limit
$250,000Per financial year, under the RBI's Liberalised Remittance Scheme.

Tax for Indian residents

TCS on remittance
20%Collected by your bank on LRS remittances above ₹10 lakh in a financial year. The TCS is adjustable against your income-tax liability.Adjusting TCS against your tax
Capital gains in India
12.5% or slab rateGains on shares held for more than 24 months are long-term and taxed at 12.5%. Gains on shares held for 24 months or less are short-term and taxed at your income-tax slab rate.Capital gains explained
Dividends
NoneNuCana does not currently pay a dividend. If it starts, dividends are taxed at your slab rate in India.Dividend tax explained

Custody. Shares are held in your own name at Interactive Brokers LLC and are SIPC-insured up to $500,000 in total, including $250,000 for cash.

FAQs

Can Indian residents buy NuCana stock?

Yes. NuCana (NCNA) has been listed on NASDAQ since 2017, in the Biotechnology industry, and Indian residents can buy it through Paasa. You fund the account from your Indian bank under the RBI's Liberalised Remittance Scheme and the money is converted to US dollars. Shares are held in your own name at Interactive Brokers LLC and are SIPC-insured up to $500,000 in total, including $250,000 for cash.

How much does one NuCana share cost in rupees?

One NuCana share is $1.28 — about ₹123 at a USD/INR rate of 95.88 on 26 Sep 2026. Both the NuCana price and the rupee rate move during the day, so the rupee cost changes with them.

What are the LRS and TCS rules for buying NuCana from India?

Remit up to $250,000 per financial year under the RBI's Liberalised Remittance Scheme (LRS). Banks collect 20% tax at source on LRS remittances above ₹10 lakh in a financial year; the TCS is adjustable against your income-tax liability. FX and the LRS declaration are handled by your bank when you fund your account.

Can I buy whole shares of NuCana?

Yes. One NuCana share is $1.28, and you can buy as many whole shares as you like. You can also buy by amount rather than by quantity: there is no minimum trade size, and Paasa supports fractional investing in NuCana.

How are gains on NuCana shares taxed in India?

The US does not levy capital gains tax on shares for Indian residents, so the tax is an India-side one. Gains on shares held for more than 24 months are long-term and taxed at 12.5%. Gains on shares held for 24 months or less are short-term and taxed at your income-tax slab rate. The gain is computed in rupees using the USD/INR rate on the purchase and the sale date, so the rupee move counts alongside the NuCana price. Paasa issues a capital-gains statement for your return.

Does NuCana pay a dividend?

No. NuCana does not currently pay a dividend, so holding it produces no dividend income to declare in India. If it starts paying one, the Indian treatment is the usual one — dividends are taxed at your slab rate in India — and Paasa's dividend report would show the gross amount and any tax withheld.

When can I trade NuCana from India?

NASDAQ trades 7:00 pm – 1:30 am IST in Indian time, so the close lands after midnight. The window shifts to 8:00 pm – 2:30 am IST when the US is on standard time. Orders can only execute during that window.

Is NuCana a United States company, and does that change how it is taxed?

NuCana trades on NASDAQ in US dollars, but the company is domiciled in United Kingdom. NuCana trades as an American Depositary Receipt rather than an ordinary share. Some non-US companies list in the US through American Depositary Receipts, which can carry dividend withholding at the company's home-country rate. Your India-side capital-gains treatment is the same either way.

Do I have to declare NuCana shares in my Indian tax return?

Yes. Foreign shares held on 31 March must be reported in Schedule FA of your Indian income-tax return. Paasa gives you a Schedule FA-ready statement listing your NuCana holding, its cost and its closing value.

How do I sell NuCana and bring the money back to India?

You sell during market hours (7:00 pm – 1:30 am IST) and the proceeds settle in USD in your Paasa account. From there you can hold the balance, reinvest, or repatriate. Funds can be withdrawn in any currency to any bank account in your own name. Whether the sale is short- or long-term is decided by the 24-month holding period.