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4528JPXMarket closedOpens 9:00am JST

Ono Pharmaceutical Co., Ltd.

¥2,333.50Last updated
-¥76.00 (3.15%)Past day
Timezone

Ono Pharmaceutical Co., Ltd. (JPX: 4528) is trading at ¥2,333.50, about ₹1,425 at today's JPY/INR rate, as of 29 Sep 2026, 2:30 AM ET, down 3.15% today. Indian residents can buy Ono Pharmaceutical from India on Paasa under the RBI's Liberalised Remittance Scheme.

Quote

Open:¥2,388.00
Previous close:¥2,409.50
Volume:1.62M

Today's low

¥2,331.00

Today's high

¥2,388.50

52 week low

¥1,678.00

52 week high

¥2,674.50

4528 opened at ¥2,388.00, closed previously at ¥2,409.50, and has traded between ¥1,678.00 and ¥2,674.50 over the past 52 weeks.

About

Ono Pharmaceutical Co., Ltd., along with its affiliated companies, is engaged in the global development, manufacturing, procurement, and sale of a diverse range of pharmaceutical products and diagnostic tools. Its diverse oncology portfolio includes OPDIVO intravenous infusions, KYPROLIS for injection, MEKTOVI, VELEXBRU, and ADLUMIZ tablets, along with BRAFTOVI capsules, all prescribed for various malignant tumors. It also provides EMEND capsules and PROEMEND intravenous injections to alleviate chemotherapy-induced nausea and vomiting, and DEMSER capsules for managing symptoms in pheochromocytoma patients. Beyond oncology, the company's offerings span multiple therapeutic areas. For metabolic disorders, it supplies GLACTIV and FORXIGA tablets for type 2 diabetes. Cardiovascular health is supported by ONOACT injections for tachyarrhythmia, CORALAN for chronic heart failure, and OPALMON tablets addressing peripheral circulatory disorders. Autoimmune conditions like rheumatoid arthritis are treated with ORENCIA injections. Neurological therapies include RIVASTACH patches for Alzheimer's disease and ONGENTYS tablets for Parkinson's disease. Other notable products are PARSABIV intravenous injections for dialysis patients, STAYBLA tablets for overactive bladder, ONON capsules and dry syrups for bronchial asthma and allergic rhinitis, and RECALBON tablets for osteoporosis, with JOYCLU intra-articular injection available to improve joint function. Moreover, the company is heavily invested in research and development, with a pipeline targeting a wide array of diseases. This includes various malignancies such as esophageal, urothelial, Hodgkin's lymphoma, ovarian, bladder, prostate, hepatocellular, pancreatic, biliary tract, gastric, thyroid, colorectal, melanoma, acute myeloid leukemia, non-small cell lung cancer, and virus-positive/negative solid tumors, as well as primary central nervous system lymphoma. Beyond cancer, its developmental efforts extend to myelodysplastic syndrome, polymyositis/dermatomyositis, tachyarrhythmia, pemphigus, generalized scleroderma, enthesopathy, diabetic polyneuropathy, neurodegenerative and autoimmune disorders, narcolepsy, and thrombosis. Established in 1717, the company maintains its corporate headquarters in Osaka, Japan.

Country
JP
CEO
Gyo Sagara
Exchange listed on
JPX
Industry
Drug Manufacturers - General
Base currency
JPY
Full Time Employees
4,206
Sector
Healthcare
IPO date
04/01/2001

Key statistics

Avg. volume

1.61M

Market cap

¥1.10T

P/E Ratio

14.38

Price-to-sales ratio

2.17

Enterprise value

¥994.09B

Free cash flow yield

11.74%

Debt-to-equity ratio

0.14

Return on equity

9.08%

ROIC

8.46%

Beta

0.14

Dividend yield

3.43%

Last dividend

¥80.00

Financial overview

Revenue

¥515.78B

Earnings per share

¥148.49

Free cash flow

¥130.80B

Net profit margin

15.13%

Gross margin

73.56%

EBITDA

¥133.94B

Revenue growth

5.94%

Similar securities

This is not an investment recommendation

How to buy Ono Pharmaceutical from India

Indian residents can buy Ono Pharmaceutical shares through Paasa in four steps. Funds leave India under the RBI's Liberalised Remittance Scheme and the shares are held in your own name with Interactive Brokers.

  1. Open a Paasa account

    Complete digital KYC with your PAN, Aadhaar and address proof. Your brokerage account is opened in your own name with Interactive Brokers.

  2. Add funds under LRS

    Transfer INR from your Indian bank account. Your bank reports the remittance under the RBI's Liberalised Remittance Scheme and converts it to US dollars and then to JPY.

  3. Search for Ono Pharmaceutical and place an order

    Find Ono Pharmaceutical by name or by its ticker, 4528, and choose an order type. The Tokyo Stock Exchange typically trades in units of 100 shares. Ono Pharmaceutical trades 5:30 am – 12:00 pm IST; orders can only execute during that window.

  4. Track holdings and download tax reports

    Follow your Ono Pharmaceutical position in JPY and INR, and use Paasa's capital-gains and dividend statements when you file your Indian return.

Read the full guide: how to invest in Ono Pharmaceutical from India

Trading and taxes when buying Ono Pharmaceutical from India

Trading and limits

Trading hours
9:00 am – 3:30 pm JST
LRS limit
$250,000Per financial year, under the RBI's Liberalised Remittance Scheme.

Tax for Indian residents

TCS on remittance
20%Collected by your bank on LRS remittances above ₹10 lakh in a financial year. The TCS is adjustable against your income-tax liability.Adjusting TCS against your tax
Capital gains in India
12.5% or slab rateGains on shares held for more than 24 months are long-term and taxed at 12.5%. Gains on shares held for 24 months or less are short-term and taxed at your income-tax slab rate.Capital gains explained
Dividends
Slab rateDividends are taxed at your slab rate in India. Japan withholds a preferential 10% on dividends for Indian residents under the India–Japan DTAA rather than the higher domestic rate, and the tax withheld can be claimed as a foreign tax credit in India. Ono Pharmaceutical’s current yield is 3.43%.Dividend tax explained
Estate or inheritance tax
May applyJapan levies inheritance tax on Japan-located assets such as direct stocks, with an exemption of ¥30 million plus ¥6 million per statutory heir.Estate tax explained

Custody. Shares are held in your own name at Interactive Brokers, segregated from Paasa's own assets.

FAQs

Can Indian residents buy Ono Pharmaceutical stock?

Yes. Ono Pharmaceutical (4528) has been listed on the Tokyo Stock Exchange since 2001, in the Drug Manufacturers - General industry, and Indian residents can buy it through Paasa. You fund the account from your Indian bank under the RBI's Liberalised Remittance Scheme and the money is converted to US dollars and then to JPY. Shares are held in your own name at Interactive Brokers, segregated from Paasa's own assets.

How much does one Ono Pharmaceutical share cost in rupees?

One Ono Pharmaceutical share is ¥2,333.50 — about ₹1,425 at a JPY/INR rate of 0.6107 on 28 Sep 2026. Both the Ono Pharmaceutical price and the rupee rate move during the day, so the rupee cost changes with them.

What are the LRS and TCS rules for buying Ono Pharmaceutical from India?

Remit up to $250,000 per financial year under the RBI's Liberalised Remittance Scheme (LRS). Banks collect 20% tax at source on LRS remittances above ₹10 lakh in a financial year; the TCS is adjustable against your income-tax liability. FX and the LRS declaration are handled by your bank when you fund your account.

What is the minimum I can buy of Ono Pharmaceutical?

The Tokyo Stock Exchange typically trades in units of 100 shares.

How are gains on Ono Pharmaceutical shares taxed in India?

Japan generally does not levy capital gains tax on non-resident individual investors, so the tax is an India-side one. Gains on shares held for more than 24 months are long-term and taxed at 12.5%. Gains on shares held for 24 months or less are short-term and taxed at your income-tax slab rate. The gain is computed in rupees using the JPY/INR rate on the purchase and the sale date, so the rupee move counts alongside the Ono Pharmaceutical price. Paasa issues a capital-gains statement for your return.

Does Ono Pharmaceutical pay a dividend, and how is it taxed in India?

Yes. Ono Pharmaceutical pays a dividend and the current yield is 3.43%; the last declared dividend was ¥80.00 per share, about ₹48.85. Dividends are taxed at your slab rate in India. Japan withholds a preferential 10% on dividends for Indian residents under the India–Japan DTAA rather than the higher domestic rate, and the tax withheld can be claimed as a foreign tax credit in India. Paasa's dividend report lists the gross dividend and any tax withheld for each payment.

When can I trade Ono Pharmaceutical from India?

The Tokyo Stock Exchange trades 5:30 am – 12:00 pm IST in Indian time. It also halts for lunch, 8:00 am – 9:00 am IST. Orders can only execute during that window.

Is there estate or inheritance tax on Ono Pharmaceutical shares held from India?

Japan levies inheritance tax on Japan-located assets such as direct stocks, with an exemption of ¥30 million plus ¥6 million per statutory heir. It applies to your overall holdings in that jurisdiction rather than to any one position.

Do I have to declare Ono Pharmaceutical shares in my Indian tax return?

Yes. Foreign shares held on 31 March must be reported in Schedule FA of your Indian income-tax return. Paasa gives you a Schedule FA-ready statement listing your Ono Pharmaceutical holding, its cost and its closing value.

How do I sell Ono Pharmaceutical and bring the money back to India?

You sell during market hours (5:30 am – 12:00 pm IST) and the proceeds settle in JPY in your Paasa account. From there you can hold the balance, reinvest, or repatriate. Funds can be withdrawn in any currency to any bank account in your own name. Whether the sale is short- or long-term is decided by the 24-month holding period.