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SBIOAMEXMarket closedOpens 9:30am ET

ALPS Medical Breakthroughs ETF

$55.62Last updated
-$0.30 (0.53%)Past day
Timezone

ALPS Medical Breakthroughs ETF (AMEX: SBIO) is an exchange-traded fund listed on NYSE Arca, trading at $55.62 (about ₹5,244 a unit) as of 13 Nov 2026, 3:59 PM ET. It has an expense ratio of 0.5% and holds 103 securities. Indian residents can buy SBIO through Paasa under the RBI's Liberalised Remittance Scheme.

Quote

Open:$55.04
Previous close:$55.91
Volume:11.59K

Today's low

$54.38

Today's high

$55.81

52 week low

$44.80

52 week high

$70.85

SBIO opened at $55.04, closed previously at $55.91, and has traded between $44.80 and $70.85 over the past 52 weeks.

About

The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small and mid-cap stocks of biotechnology companies that have one or more drugs in either Phase II or Phase III of the U.S. Food and Drug Administration clinical trials.

Issuer
ALPS Funds
Exchange listed on
AMEX
Asset class
Equity
Base currency
USD
Domicile
United States
Dividends
—
Launched
2014
ISIN
US00162Q5936

Key statistics

Expense ratio

0.5%

Assets (AUM)

$186.3M

Holdings

103

NAV

$55.60

Avg. volume

38.04K

1-year price change

+20.61%

5-year price change

+19.89%

Price change excludes dividends.

Top 10 holdings

1. Oruka Therapeutics Inc.
4.6%
2. CG oncology Inc.
4.3%
3. VeraDermics Inc.
3.6%
4. Dianthus Therapeutics Inc.
3.4%
5. Edgewise Therapeutics Inc.
3.3%
6. Travere Therapeutics Inc.
3.1%
7. Definium Therapeutics Inc.
2.8%
8. Relay Therapeutics Inc.
2.6%
9. Xenon Pharmaceuticals Inc.
2.6%
10. Amylyx Pharmaceuticals Inc.
2.5%

SBIO holds 103 securities in total. These 10 are 32.8% of the fund.

Where the money is invested

Countries

United States
91.9%
Canada
2.6%
China
1.9%
Netherlands
1.6%
United Kingdom
1.5%
Switzerland
0.3%

How to buy SBIO from India

Indian residents can buy SBIO units through Paasa in four steps. Funds leave India under the RBI's Liberalised Remittance Scheme and the units are held in your own name with Interactive Brokers. Read the full guide: how to invest in SBIO from India

  1. Open your Paasa account

    KYC takes a few minutes: PAN, Aadhaar and address proof. Your brokerage account is opened in your own name with Interactive Brokers.

  2. Add funds from your Indian bank account

    Remit up to $250,000 a year under the RBI's Liberalised Remittance Scheme. Your bank converts the rupees to US dollars at its rate on the day you remit.

  3. Search SBIO and buy

    Find the fund by its ticker, SBIO, on NYSE Arca, and place your order. Fractional units are available and there is no minimum trade size, so you can buy by amount.

  4. Track holdings and download tax reports

    Follow your SBIO position in USD and INR, and use Paasa's tax statements when you file your Indian return.

Trading and taxes when buying SBIO from India

Trading and limits

Trading hours
9:30 am – 4:00 pm ET
LRS limit
$250,000Per financial year, under the RBI's Liberalised Remittance Scheme.

Tax for Indian residents

TCS on remittance
20%Collected by your bank on LRS remittances above ₹10 lakh in a financial year. The TCS is adjustable against your income-tax liability.Adjusting TCS against your tax
Capital gains in India
12.5% or slab rateGains on foreign ETF units held for more than 24 months are long-term and taxed at 12.5% without indexation. Gains on units held for 24 months or less are short-term and taxed at your income-tax slab rate.Capital gains explained
US estate tax
May applyUS-situs assets such as US-listed shares can be exposed to US estate tax for non-US persons.US estate tax calculator

FAQs

What is the SBIO price today?

ALPS Medical Breakthroughs ETF (SBIO) last traded at $55.62 on NYSE Arca, as of 13 Nov 2026, 3:59 PM ET. That is ₹5,244 a unit at the 13 Nov 2026 USD/INR rate.

When does SBIO trade, in Indian time?

NYSE Arca trades 8:00 pm – 2:30 am IST, so the close lands after midnight. The window shifts to 7:00 pm – 1:30 am IST when the US is on daylight time. Orders can only execute during that window.

How big is SBIO, and what does it cost to hold?

ALPS Medical Breakthroughs ETF manages about $186.3M. Its expense ratio is 0.5% a year, deducted inside the fund. It launched in 2014.

What are SBIO's largest holdings?

The top three are Oruka Therapeutics Inc. (4.6%), CG oncology Inc. (4.3%) and VeraDermics Inc. (3.6%). SBIO's 10 largest positions make up 32.8% of the fund.

How are gains on SBIO taxed in India?

Units held for more than 24 months are long-term and taxed at 12.5% without indexation; units held for 24 months or less are taxed at your income-tax slab rate. The gain is worked out in rupees, so the currency move counts.

Can I buy fractional units of SBIO?

Yes. You can buy SBIO by amount rather than by whole unit, and there is no minimum trade size.

How has SBIO performed?

SBIO's price is up 20.6% over the past year and up 19.9% over five years. These figures are price change only and exclude dividends; past performance does not guarantee future returns.